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These mutations therefore disproportionately affect individuals with ancestry from malaria endemic regions, namely Africa, the Middle East, Southeast Asia, and the Mediterranean

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Neutrophils serve as short-lived innate immune cells that constitute the first line of defense against microbial infections

Due to intrinsic Cpf1 ribonuclease activity that facilitates crRNA processing and an array of donor DNA sequences for homology-directed repair of double-strand breaks generated by Cpf1, the multi-CRISPR/Cpf1 system is more efficient for multiplex deletion of up to four genes (Jimnez et al., 2019a)

Other health issues Apart from liver damage and immune suppression, aflatoxins are associated with several other health issues, both acute and chronic, depending on the level and duration of exposure